Keiji Kamohara
Papers
1
Total Citations
295
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About
Dr. Keiji Kamohara is a pioneering figure in cardiovascular tissue engineering, best known for his groundbreaking work in developing scaffold-free vascular grafts using bio-3D printing technology. His research focuses on creating functional, living tubular tissues that can integrate with the body's native vasculature, addressing a critical unmet need for small-caliber vascular prostheses. In his landmark 2015 study, cited over 295 times, Dr. Kamohara demonstrated that scaffold-free tubular tissues created by a bio-3D printer undergo significant remodeling and endothelialization when implanted in rat aortae. This work represents a major contribution to the field, as it overcomes the limitations of synthetic grafts—which lack endothelial cells essential for regulating platelet activation, leukocyte adhesion, thrombosis, and vasomotor tone. By enabling the formation of a functional endothelium, his approach holds promise for reducing graft failure and improving long-term patency. Dr. Kamohara's innovative methodology has set a new standard for vascular tissue engineering, inspiring further research into biofabrication and regenerative medicine. His achievements underscore the potential of 3D bioprinting to revolutionize cardiovascular surgery and tissue replacement therapies.
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