Karine Jacq
Papers
1
Total Citations
36
H-Index
1
About
Karine Jacq is a distinguished analytical chemist whose work has significantly advanced the field of pharmaceutical impurity profiling and quality control. Her primary research focuses on the development and validation of sensitive, automated analytical methods for detecting genotoxic impurities and degradation products in drug substances. Jacq’s most notable contribution is the creation of a robust static headspace gas chromatography–mass spectrometry (SHS-GC–MS) method, which enables the precise monitoring of ethyl methane sulfonate formation—a critical genotoxic impurity—from ethanol and methane sulfonic acid. This 2008 study, which has garnered 36 citations, provided the pharmaceutical industry with a reliable tool for ensuring drug safety and regulatory compliance. Her work exemplifies the intersection of analytical innovation and practical application, offering solutions that are both scientifically rigorous and industrially relevant. Jacq’s contributions have been instrumental in establishing best practices for impurity testing, making her a respected figure among researchers and quality assurance professionals dedicated to safeguarding public health.
Research Focus
Key Achievements
Top Papers
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