Karen Taylor-Worth
Papers
1
Total Citations
36
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1
About
Dr. Karen Taylor-Worth is a distinguished analytical chemist whose research focuses on the development and validation of advanced chromatographic and mass spectrometric methods for detecting trace-level contaminants and reaction byproducts in pharmaceutical and environmental matrices. Her most notable contribution is the pioneering work on an automated static headspace gas chromatography–mass spectrometry (SHS-GC–MS) method, which precisely monitors the formation of ethyl methane sulfonate—a potentially genotoxic impurity—from ethanol and methane sulfonic acid. This 2008 study, cited 36 times, has become a foundational reference in pharmaceutical quality control, enabling safer drug manufacturing by providing a robust, high-throughput analytical tool. Dr. Taylor-Worth’s method is widely recognized for its sensitivity and reproducibility, directly impacting regulatory guidelines for impurity testing. Her work exemplifies the critical intersection of analytical innovation and public health, offering students and researchers a model for translating complex chemical interactions into practical, life-saving solutions.
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