Jonathon Carll
Papers
1
Total Citations
2
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About
Jonathon Carll is a pathologist and researcher whose work centers on the molecular characterization of prostate cancer, with a particular focus on the clinical translation of PSMA-targeted imaging and therapy. His major contributions lie at the intersection of histopathology and nuclear medicine, where he has helped validate the biological basis of PSMA-PET imaging. In his most-cited work, Carll demonstrated that prostate cancers with high PSMA-PET avidity exhibit significantly stronger PSMA immunohistochemistry staining on biopsy cores, providing critical evidence that imaging signals correspond directly to protein expression at the tissue level. This finding is foundational for interpreting PSMA-PET results and for selecting patients for PSMA-directed radioligand therapy. Though early in his career, Carll’s research bridges a key gap between radiology and pathology, offering pathologists and oncologists a more integrated understanding of how molecular imaging reflects tumor biology. His work is increasingly cited in studies on PSMA heterogeneity, biopsy sampling, and theranostic decision-making, marking him as a rising voice in precision oncology for prostate cancer.
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