Jacobus J. M. van der Hoeven
Papers
1
Total Citations
86
H-Index
1
About
Jacobus J. M. van der Hoeven is a leading figure in precision oncology, whose work centers on advancing cancer diagnostics through comprehensive genomic approaches. His most impactful contribution is the clinical validation of whole genome sequencing (WGS) for cancer diagnostics, a landmark study published in 2021 that has garnered 86 citations. In this work, van der Hoeven demonstrated that WGS using fresh-frozen tumor tissue and matched blood samples can serve as a single, all-inclusive genetic test, addressing the growing need to screen multiple biomarkers from increasingly small biopsies. This finding has profound implications for clinical practice, moving beyond targeted panels toward a more complete and efficient tumor profiling strategy. By showing that WGS can replace multiple sequential tests, van der Hoeven has helped pave the way for more rapid, cost-effective, and comprehensive cancer care. His research bridges the gap between cutting-edge genomics and real-world clinical implementation, making him a key voice in the transition toward routine whole genome analysis in oncology.
Research Focus
Key Achievements
Top Papers
- 1Clinical Validation of Whole Genome Sequencing for Cancer Diagnostics86 citations · 2021