Guohong Wu

Papers

Total Citations

H-Index

About

Guohong Wu is a structural biologist whose research focuses on the computational design and assembly of helical proteins, with a particular emphasis on understanding and engineering hydrophobic packing interactions. In his most-cited work, "Iterative Assembly of Helical Proteins by Optimal Hydrophobic Packing" (2008), Wu introduced a novel iterative approach that systematically optimizes hydrophobic core packing to guide the self-assembly of helical protein structures. This contribution has been foundational for researchers seeking to design stable, functional proteins from scratch, offering a robust framework for predicting and controlling protein folding and assembly. With over 10 citations, this paper has influenced subsequent studies in de novo protein design and biomolecular engineering. Wu’s work bridges computational modeling and experimental validation, providing tools that enable the rational construction of proteins with tailored properties. His achievements underscore a commitment to advancing the frontiers of protein science, making his research a valuable resource for students and scientists exploring the principles of protein structure and design.