Frank D. Kolodgie
Papers
1
Total Citations
5
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1
About
Dr. Frank D. Kolodgie is a leading pathologist whose research has fundamentally shaped our understanding of coronary artery disease and sudden cardiac death. His key contributions lie in vascular biology, specifically the mechanisms of plaque progression, thrombosis, and the role of microcalcifications in vulnerable plaques. Dr. Kolodgie is perhaps best known for his seminal work on the "vulnerable plaque" concept, demonstrating that thin-cap fibroatheromas are the primary substrate for acute coronary syndromes. His studies, often utilizing human autopsy specimens, have provided critical insights into the natural history of atherosclerosis, with his most cited papers collectively amassing over 10,000 citations. He has been instrumental in characterizing the role of intraplaque hemorrhage and the vasa vasorum in plaque destabilization. Beyond his foundational research, Dr. Kolodgie has contributed to translational studies, including robotic-assisted PCI in swine, showcasing his commitment to bridging basic pathology with clinical innovation. His work remains essential reading for cardiologists and vascular biologists alike.
Research Focus
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Top Papers
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