Eugenio Garofalo

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About

Eugenio Garofalo is a leading anesthesiology and critical care researcher whose work focuses on optimizing mechanical ventilation strategies during surgery and in intensive care. His primary research areas include intraoperative lung protection, positive end-expiratory pressure (PEEP) titration, and the interplay between respiratory mechanics and patient outcomes. Garofalo’s major contribution lies in challenging conventional ventilation protocols by investigating individualized PEEP settings. In his highly cited 2020 study, “Esophageal Pressure Versus Gas Exchange to Set PEEP During Intraoperative Ventilation,” he pioneered a comparison between esophageal pressure-guided PEEP and traditional gas exchange methods in patients undergoing pelvic robotic surgery. This work demonstrated that personalized PEEP, based on transpulmonary pressure, could improve respiratory mechanics without compromising oxygenation, offering a safer approach for patients in steep Trendelenburg position. With over 30 citations, this study has influenced subsequent guidelines on intraoperative ventilation. Garofalo’s research continues to shape how clinicians balance lung protection with surgical needs, making him a key voice in perioperative medicine and a valuable resource for students and clinicians seeking evidence-based strategies for ventilator management.