Dan Ruan

University of California, Los Angeles, Stanford University

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About

Dan Ruan is a leading researcher in radiation oncology physics, with a primary focus on advancing robotic radiotherapy and optimization algorithms for cancer treatment. Her work bridges the gap between theoretical dosimetric gains and practical clinical implementation, particularly through the development of non-coplanar radiotherapy techniques on conventional C-arm linear accelerators. Ruan’s seminal 2013 paper, "Feasibility of prostate robotic radiation therapy on conventional C-arm linacs," with 44 citations, demonstrated the viability of using robotic platforms to overcome clearance and motion coordination challenges, enabling precise, many-isocenter optimization for prostate cancer. Her 2019 study on many-isocenter optimization for robotic radiotherapy further refined these methods, addressing the complex gantry and couch dynamics that hinder widespread adoption. Ruan also contributed to multi-criteria optimization with a linear approach to dose-volume constraints, offering a computationally efficient framework for treatment planning. Her work has been instrumental in making advanced, high-precision radiotherapy more accessible, with potential to improve outcomes for patients with complex tumors. Ruan’s research continues to shape the future of automated, adaptive radiation therapy.