Colleen Shea
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1
Total Citations
52
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1
About
Colleen Shea is a pioneering radiochemist whose work has significantly advanced the quantitative accuracy of positron emission tomography (PET) imaging. Her research centers on the development of automated systems for radiotracer production and the precise measurement of plasma input functions—a critical component for kinetic modeling in PET studies. Shea’s most notable contribution, detailed in her highly cited 1995 paper "Plasma input function determination for PET using a commercial laboratory robot" (52 citations), introduced a novel method to automate the labor-intensive process of blood sampling and analysis. By integrating a commercial laboratory robot, she enabled more reproducible and efficient collection of arterial input data, directly improving the reliability of PET quantification in clinical and research settings. This work has been foundational for subsequent automation efforts in nuclear medicine, reducing human error and enhancing throughput. Shea’s achievements underscore her role in bridging robotics and radiochemistry, making her a key figure in the evolution of PET imaging technology. Her contributions continue to influence studies in neuroscience, oncology, and cardiology, where accurate tracer kinetics are essential.
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