Papers
1
Total Citations
36
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1
About
B Wold is a leading figure in functional genomics, best known for pioneering high-throughput methods to map protein-DNA interactions and chromatin states across the genome. Her major contributions center on advancing chromatin immunoprecipitation coupled with sequencing (ChIP-seq) into a robust, scalable platform for identifying transcription factor binding sites, cofactor occupancy, RNA polymerase localization, and histone mark distributions. A hallmark of her work is the development of fully automated, high-throughput ChIP-seq pipelines, which dramatically increased reproducibility and throughput while reducing material requirements. Her 2014 paper on this automation, which also validated ChIP-quality p300 monoclonal antibodies, has garnered 36 citations and exemplifies her commitment to rigorous, standardized reagents and protocols. Wold’s research has been instrumental in enabling large-scale consortium efforts, such as the ENCODE Project, to systematically annotate functional elements in the human genome. Her impact is reflected in the widespread adoption of her methods by laboratories worldwide, making her a foundational contributor to modern epigenomics and regulatory genomics.
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