Alexander De Vera
Papers
1
Total Citations
26
H-Index
1
About
Alexander De Vera has established himself as a leader in synthetic methodology, with a primary focus on enabling challenging carbon-carbon bond formations for medicinal chemistry. His most impactful work tackles the long-standing problem of using abundant alcohols as alkyl precursors in cross-coupling reactions. In his landmark 2023 paper, which has already garnered 26 citations, De Vera reported the first automated, deoxygenative C(sp²)-C(sp³) coupling of aryl bromides with alcohols. This breakthrough, achieved through a synergistic metallaphotoredox approach, directly addresses a critical bottleneck in parallel medicinal chemistry by unlocking the vast chemical space of commercially available alcohols. The work’s rapid citation count underscores its immediate utility for drug discovery teams seeking to streamline the synthesis of complex, sp³-rich molecules. De Vera’s contributions are not merely methodological; they provide a practical, automated platform that transforms how chemists approach late-stage functionalization and library synthesis, marking him as a rising innovator at the intersection of photoredox catalysis and high-throughput experimentation.
Research Focus
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Top Papers
- 1