Yuri E. M. van der Burgt

Leiden University Medical Center

Papers

5

Total Citations

202

H-Index

5

About

Yuri E. M. van der Burgt is a prominent analytical scientist whose research sits at the intersection of mass spectrometry, proteomics, and glycomics, with a particular focus on advancing clinical diagnostics through cutting-edge analytical technologies. His most celebrated contribution — an automated, high-throughput MALDI-TOF-MS method for plasma N-glycome analysis featuring linkage-specific sialic acid esterification — has garnered 92 citations and represents a landmark advance in making complex glycosylation profiling both scalable and reproducible. This work underscores his commitment to transforming sophisticated biochemical techniques into practical, high-throughput tools. Beyond glycomics, van der Burgt has been a vocal advocate for quantitative protein mass spectrometry in precision diagnostics, arguing — in a highly cited 2021 paper — that MS-based tests are uniquely positioned to address unmet clinical needs where traditional immunoassays fall short. His earlier work on quality control frameworks for serum peptide profiling and standardized solid-phase extraction protocols further demonstrates his systematic approach to improving data reliability and workflow automation in clinical proteomics. His research on breast cancer biomarker discovery adds a direct translational dimension to his portfolio. Collectively, his contributions have meaningfully shaped how the field approaches robust, clinically actionable molecular profiling.

Research Focus

Key Achievements

5
H-Index
5
Papers
202
Total Citations
40
Avg Citations/Paper
🏆 Most Cited Paper
Automation of High-Throughput Mass Spectrometry-Based Plasma <i>N</i>-Glycome Analysis with Linkage-Specific Sialic Acid Esterification
92 citations · 2015
📈 Most Prolific Year: 2012 (2 Papers)
🤝 Key Collaborators: 24
🏛 Institutions: Leiden University Medical Center

Top Papers

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Key Collaborators

Contact & Links

Available for collaboration
Content generated · 17 days ago