Marco R. Bladergroen

Leiden University Medical Center

Papers

4

Total Citations

174

H-Index

4

About

Marco R. Bladergroen is a bioanalytical researcher whose work sits at the intersection of mass spectrometry, proteomics, and glycomics, with a particular focus on developing automated, high-throughput analytical platforms for clinical and biological applications. His most significant contribution, garnering 92 citations, involves the automation of plasma N-glycome analysis using MALDI-TOF mass spectrometry with linkage-specific sialic acid esterification — a methodological advance that dramatically improved the comprehensiveness and reproducibility of glycan profiling at scale. This work reflects his broader commitment to transforming technically demanding biochemical analyses into robust, standardized workflows suitable for large cohort studies. Bladergroen has also made notable contributions to imaging mass spectrometry, pushing the field toward high-throughput capabilities, and has developed quality control frameworks based on isotopic distributions for serum peptide profiling — work that addresses a critical bottleneck in large-scale proteomics data integrity. His research on standardized solid-phase extraction procedures further underscores his dedication to method harmonization across body fluid proteomics. Collectively, his publications demonstrate a consistent effort to bridge methodological innovation with practical scalability, making his work particularly valuable to researchers in clinical biomarker discovery and translational medicine.

Research Focus

Key Achievements

4
H-Index
4
Papers
174
Total Citations
44
Avg Citations/Paper
🏆 Most Cited Paper
Automation of High-Throughput Mass Spectrometry-Based Plasma <i>N</i>-Glycome Analysis with Linkage-Specific Sialic Acid Esterification
92 citations · 2015
📈 Most Prolific Year: 2015 (1 Papers)
🤝 Key Collaborators: 19
🏛 Institutions: Leiden University Medical Center

Top Papers

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Key Collaborators

Contact & Links

Available for collaboration
Content generated · 13 days ago