Yu‐Luan Chen

Papers

Total Citations

H-Index

About

Yu-Luan Chen is a distinguished analytical chemist whose research has significantly advanced bioanalytical methods for pharmaceutical and clinical applications. Chen’s primary contributions lie in the development of highly sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) techniques for the quantification of drugs and their metabolites in biological matrices. A landmark study, "Simultaneous determination of hydrocodone and hydromorphone in human plasma by liquid chromatography with tandem mass spectrometric detection" (2002, 32 citations), exemplifies this work, providing a robust, validated method for monitoring these opioids in plasma—critical for pharmacokinetic studies and therapeutic drug monitoring. This research has been instrumental in improving the accuracy and efficiency of drug analysis, supporting both clinical research and forensic toxicology. Chen’s methodological innovations have enabled precise, simultaneous measurements of structurally similar compounds, reducing analysis time and enhancing data reliability. With a career focused on bridging analytical chemistry and pharmacology, Chen’s work continues to influence the development of safer, more effective drug therapies, making their contributions essential for students and researchers in pharmaceutical sciences.