Marie Katrine Klose Nielsen
Papers
3
Total Citations
64
H-Index
3
About
Marie Katrine Klose Nielsen is a forensic toxicologist whose research focuses on the development and validation of advanced analytical methods for detecting and quantifying drugs and pharmaceuticals in biological matrices. Her work has made significant contributions to postmortem toxicology and drug-facilitated crime investigations, combining ultra-high-performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) with innovative sample preparation strategies to improve accuracy and efficiency in forensic casework. Nielsen's most cited work (37 citations) introduced a fully automated solid-phase extraction method capable of quantifying 30 pharmaceuticals in postmortem blood and brain tissue, substantially reducing manual laboratory error. She later extended this framework to muscle tissue analysis (22 citations), providing forensic pathologists with a validated alternative when blood is unavailable — a critical advancement in complex death investigations. More recently, her research has addressed drug-facilitated sexual assault (DFSA), employing automated enzymatic hydrolysis to broaden the detection spectrum of substances in urine samples. Across her publications, Nielsen demonstrates a consistent commitment to translating methodological innovation into practical forensic applications, improving both the reliability and scope of toxicological screening in some of the most sensitive and consequential legal contexts.
Research Focus
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