Inge M. Mulder
Papers
1
Total Citations
55
H-Index
1
About
Inge M. Mulder has made foundational contributions to the molecular diagnosis of Duchenne and Becker muscular dystrophy (DMD/BMD), focusing on the detection of subtle mutations in the dystrophin gene. Her key research areas include mutation scanning technologies, particularly denaturing gradient gel electrophoresis (DGGE), and the genetic characterization of neuromuscular disorders. Mulder’s most cited work, a 2003 study on DGGE-based whole-gene mutation scanning, has garnered 55 citations and provided a critical tool for identifying the small mutations responsible for the 30-35% of DMD cases not explained by large deletions or duplications. This work significantly improved diagnostic yield for patients and families, enabling more accurate genetic counseling and carrier detection. Beyond this, her research has advanced understanding of mutation spectra in dystrophinopathies, directly impacting clinical genetics. Mulder’s achievements include pioneering the application of DGGE to a gene of exceptional size and complexity, a technical feat that set a standard for comprehensive mutation analysis. Her contributions remain essential for researchers and clinicians working on muscular dystrophy genetics.
Research Focus
Key Achievements
Top Papers
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