Do Prophylactic Antibiotics Decrease the Rate of Urinary Tract Infections After Robot-Assisted Radical Cystectomy? A Randomized Controlled Trial

Abstract

PURPOSE: The purpose of this article was to investigate the role of prophylactic antibiotics after robot-assisted radical cystectomy (RARC) in the prevention of 90-day UTIs. MATERIALS AND METHODS: cfu/mL associated with clinical symptoms, such as fever, chills, or flank pain). Secondary end points included adverse events, 90-day infectious complications, UTI-related readmissions, and cost. RESULTS: = .007). The number needed to treat to prevent a single UTI was 4.0 (95% CI, 2.5-7.0). CONCLUSIONS: Prophylactic antibiotics for 30 days after RARC were associated with lower 90-day UTIs, infectious complications, UTI-related readmissions, and costs without an increase in adverse events.