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Do Prophylactic Antibiotics Decrease the Rate of Urinary Tract Infections After Robot-Assisted Radical Cystectomy? A Randomized Controlled Trial

Ahmed A. Hussein, Abdul Wasay Mahmood, Ali Ahmad, Holly Houenstein, Grace Harrington, Mohammad S. Khan, Dawod Abdelhaq, Zhe Jing, Kristopher Attwood, Nikolaos G. Almyroudis, Qiang Li, Khurshid A. Guru

发表年份
2025
引用次数
4

摘要

PURPOSE: The purpose of this article was to investigate the role of prophylactic antibiotics after robot-assisted radical cystectomy (RARC) in the prevention of 90-day UTIs. MATERIALS AND METHODS: cfu/mL associated with clinical symptoms, such as fever, chills, or flank pain). Secondary end points included adverse events, 90-day infectious complications, UTI-related readmissions, and cost. RESULTS: = .007). The number needed to treat to prevent a single UTI was 4.0 (95% CI, 2.5-7.0). CONCLUSIONS: Prophylactic antibiotics for 30 days after RARC were associated with lower 90-day UTIs, infectious complications, UTI-related readmissions, and costs without an increase in adverse events.

关键词

MedicineCystectomyUrinary systemRandomized controlled trialUrologyAntibioticsUrinary diversionAntibiotic prophylaxisSurgeryInternal medicine

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