Precise Control of Customized Macrophage Cell Robot for Targeted Therapy of Solid Tumors with Minimal Invasion (Small 41/2021)
Yuguo Dai, Xue Bai, Lina Jia, Hongyan Sun, Yanmin Feng, Luyao Wang, Chaonan Zhang, Yuanyuan Chen, Yiming Ji, Deyuan Zhang, Huawei Chen, Lin Feng
- Year
- 2021
- Citations
- 5
Abstract
Cell Robots for Tumor Therapy In article number 2103986, Huawei Chen, Lin Feng, and co-workers develop a cell robot system for targeted tumor therapy by converting biological cells through endocytosis of functionalized iron nanoparticles. The robot uses a combination of the macrophage's tumor-tropism and external magnetic control for navigation to tumors through the blood vessels. With the cascaded drug release, targeted killing of tumors in mice is demonstrated, with minimal effects on the normal surrounding tissues.
Keywords
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