Anaphylactoid Reactions after Indocyanine-Green Administration

Abstract

Letters and Corrections15 August 1988Anaphylactoid Reactions after Indocyanine-Green AdministrationRudolf Speich, MD, Barbara Saesseli, MD, Ulrich Hoffmann, MD, Klaus A. Neftel, MD, Juerg Reichen, MDRudolf Speich, MDSearch for more papers by this author, Barbara Saesseli, MDSearch for more papers by this author, Ulrich Hoffmann, MDSearch for more papers by this author, Klaus A. Neftel, MDSearch for more papers by this author, Juerg Reichen, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-109-4-345_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor: Indocyanine-green is used for determination of cardiac output, liver function testing, chorioidal angiography, and capillary microscopy. We report three cases of patients with anaphylactoid reactions to indocyanine-green, which together with reports in the literature suggest a dose-dependent pseudoallergic mechanism, rather than a true immune mechanism.A 49-year-old man received indocyanine-green, 5 mg/kg body weight for capillary microscopy. Within 10 seconds, he developed flush, dyspnea, and shock.A 56-year-old man received indocyanine-green, 0.5 mg/kg for liver function testing. Within 1 minute, he developed acute bronchospasm, hypotension, and cardiorespiratory arrest.A 62-year-old man received indocyanine-green, 0.5 mg/kg for liver...References1. MichieWomboltCarrettaZenckaEgan DDRAJ. Adverse reactions associated with the administration of a tricarbocyanine dye (Cardio-green) to uremic patients. J Allergy Clin Immunol. 1971;48:235-9. CrossrefMedlineGoogle Scholar2. CarskiStallerHepnerBankaFinney TBGVR. Adverse reactions after administration of indocyanine-green. JAMA. 1978;240:635. CrossrefGoogle Scholar3. IwamuraYamanakaYamanakaNishikawa KITH. A case of complication due to indocyanine-green test. Jap J Gastroenterology. 1974;71:573-8. MedlineGoogle Scholar4. NanikawaHayashiHayashiHashimotoAmeno RTKYK. A case of fatal shock induced by indocyanine-green (ICG) test. Jap J Legal Med. 1978;32:209-14. Google Scholar5. IsekiOnoyamaFujimiOmae KKST. Shock caused by indocyanine-green dye in chronic hemodialysis patients. Clin Nephrol. 1980;14:210. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDiagnostic value of indocyanine green for sentinel lymph node mapping and lymph node metastasis in oral/oropharyngeal carcinomaTumor visualization and fluorescence angiography with indocyanine green (ICG) in laparoscopic and robotic hepatobiliary surgery – valuation of early adopters from GermanyLong-term results of fluorescence and indigo carmine blue dye-navigated sentinel lymph node biopsySentinel lymph node biopsy in patients with endometrial cancer and an indocyanine green or iodinated contrast reaction - A proposed management algorithmComparison of SPECT-CT with intraoperative mapping in cervical and uterine malignanciesRecent Developments of ICG-Guided Sentinel Lymph Node Mapping in Oral CancerThoracoscopic segmentectomy using infrared thoracoscopy with intravenous ICG method and VAL-MAP with ICGDrugs Used in OphthalmologyTo Analyze the Clinical Value of Laparoscope Hepatectomy with Indocyanine GreenIntraoperative Perfusion Assessment in Enhanced Reality Using Quantitative Optical Imaging: An Experimental Study in a Pancreatic Partial Ischemia ModelApplication of near-infrared fluorescent cholangiography using indocyanine green in laparoscopic cholecystectomySentinel lymph node mapping using ICG fluorescence and cone beam CT – a feasibility study in a rabbit model of oral cancerThe Use of Enhanced Technologies in Robotic Surgery and Its Impact on Outcomes in Rectal Cancer: A Systematic ReviewIntraoperative fluorescence imaging with indoc