Xiaojuan Du
Papers
1
Total Citations
31
H-Index
1
About
Xiaojuan Du is a leading figure in bioanalytical chemistry, with a core focus on advancing mass spectrometry techniques for clinical diagnostics. Her most-cited work, "Ultra‐fast mass fingerprinting by high‐affinity capture of peptides and proteins on derivatized poly(glycidyl methacrylate/divinylbenzene) for the analysis of serum and cell lysates" (2006, 31 citations), introduces a pioneering material-based approach to matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). Du developed novel derivatized polymer supports that enable high-affinity capture of peptides and proteins, dramatically accelerating the mass fingerprinting process. This innovation, termed material-enhanced laser desorption/ionization (MELDI), allows for ultra-fast, sensitive analysis of complex biological samples like serum and cell lysates. By simplifying sample preparation and enhancing detection, her work directly addresses the critical need for reliable diagnostic markers. Du’s contributions bridge materials science and proteomics, offering a powerful tool for disease biomarker discovery. Her research continues to influence the development of high-throughput, material-based platforms for clinical analysis, making her a key innovator in the field of bioanalytical mass spectrometry.
Research Focus
Key Achievements
Top Papers
- 1