Hong-Gang Qian
Papers
1
Total Citations
31
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1
About
Hong-Gang Qian is a leading figure in the development of advanced materials for mass spectrometry-based proteomics. His research focuses on creating high-affinity capture supports for the ultra-fast identification of peptides and proteins, directly impacting clinical diagnostics and biomarker discovery. His most cited work, "Ultra‐fast mass fingerprinting by high‐affinity capture of peptides and proteins on derivatized poly(glycidyl methacrylate/divinylbenzene) for the analysis of serum and cell lysates" (2006, 31 citations), pioneered a material-enhanced laser desorption/ionization (MELDI) approach. By engineering derivatized polymer supports, Qian enabled the rapid, sensitive, and selective enrichment of biomolecules from complex biological samples like serum and cell lysates, dramatically improving the speed and reliability of MALDI-TOF MS analysis. This innovation offers a powerful tool for discovering diagnostic markers, bridging materials science and clinical proteomics. With over 30 citations on this foundational work alone, Qian’s contributions continue to influence the design of functional materials for high-throughput protein profiling, making his research essential for students and scientists advancing precision medicine and analytical biochemistry.
Research Focus
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Top Papers
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