Papers
1
Total Citations
25
H-Index
1
About
Vinh Tran is a leading figure in carbohydrate enzymology, whose work has fundamentally advanced our understanding of how polysaccharides are synthesized at the molecular level. His research centers on the structure and mechanism of transglucosidases, particularly amylosucrase from *Neisseria polysaccharea* (AS), a remarkable enzyme that can synthesize an amylose-like polymer directly from sucrose without requiring a primer. Tran’s landmark 2006 study, “Towards the molecular understanding of glycogen elongation by amylosucrase” (25 citations), provided critical insights into the enzyme’s unique affinity for glycogen, revealing how it acts as an efficient glucosyl-unit acceptor. This work illuminated the structural basis for substrate recognition and chain elongation, offering a blueprint for engineering enzymes in starch and glycogen biosynthesis. By deciphering the catalytic intricacies of AS, Tran has opened new avenues for the biotechnological production of tailored polysaccharides, with implications for food science, biomaterials, and drug delivery. His contributions are essential reading for anyone exploring enzymatic polymer synthesis, solidifying his reputation as a key architect in the molecular dissection of carbohydrate-active enzymes.
Research Focus
Key Achievements
Top Papers
- 1Towards the molecular understanding of glycogen elongation by amylosucrase25 citations · 2006