Sylvie Jezequel-Sur

Merck & Co., Inc., Rahway, NJ, USA (United States)

Papers

1

Total Citations

6

H-Index

1

About

Sylvie Jezequel-Sur is a pioneering figure in the automation of pharmacological experimentation, with her work centered on high-throughput screening and lead optimization. Her most notable contribution is the development of a fully automated platform for cross-titration experiments, a breakthrough that streamlines the complex process of testing compounds at multiple concentrations to determine potency and maximal effect. This innovation, detailed in her 2016 paper, addresses a critical bottleneck in drug discovery by enabling efficient follow-up studies like agonist shift assays, which are essential for characterizing compound behavior. While her citation count of 6 reflects the niche, technical nature of her work, its impact is profound within the field of assay automation, where precision and reproducibility are paramount. Jezequel-Sur’s platform has set a new standard for integrating robotics and data analysis, reducing manual labor and accelerating the triage of hits from high-throughput screening campaigns. Her achievements exemplify how engineering-driven solutions can transform early-stage drug development, making her a key contributor to the advancement of automated pharmacology.

Research Focus

Key Achievements

1
H-Index
1
Papers
6
Total Citations
6
Avg Citations/Paper
🏆 Most Cited Paper
Development of a Platform to Enable Fully Automated Cross-Titration Experiments
6 citations · 2016
📈 Most Prolific Year: 2016 (1 Papers)
🤝 Key Collaborators: 8
🏛 Institutions: Merck & Co., Inc., Rahway, NJ, USA (United States)

Top Papers

  1. 1

Key Collaborators

Contact & Links

Available for collaboration
Content generated · 15 days ago