Stine T Sjaatil
Papers
1
Total Citations
22
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1
About
Stine T. Sjaatil is a clinical researcher whose work lies at the intersection of pharmacogenomics and cardiovascular medicine, with a particular focus on optimizing anticoagulation therapy. Her major contributions center on understanding how genetic variations influence individual responses to warfarin, a drug with a notoriously narrow therapeutic window. In her highly cited 2008 study, which has garnered 22 citations, Sjaatil investigated how polymorphisms in the CYP2C9 and VKORC1 genes affect warfarin dose requirements and INR stability in patients recovering from myocardial infarction. This work provided crucial evidence that genotype-guided dosing could reduce the risks of bleeding or thrombosis, paving the way for more personalized anticoagulation protocols. By bridging the gap between genetic testing and clinical practice, Sjaatil’s research has helped advance the field of precision medicine in cardiology. Her findings underscore the potential for genetic screening to improve patient safety and treatment efficacy, making her a notable contributor to the ongoing effort to tailor drug therapies to individual genetic profiles.
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