Sanaullah Khan
Papers
3
Total Citations
131
H-Index
3
About
Sanaullah Khan is a bioanalytical chemist whose research has made significant contributions to the development and optimization of sample preparation techniques for pharmaceutical analysis, particularly in the context of drug discovery and clinical pharmacokinetics. His most influential work, published in 1999 and garnering 79 citations, systematically compared plasma sample purification methods — including manual liquid-liquid extraction, automated 96-well liquid-liquid extraction, and automated 96-well solid-phase extraction — providing the field with critical guidance for high-throughput bioanalytical workflows using HPLC-MS/MS. Khan has also contributed to the bioanalytical characterization of novel therapeutics, notably developing an electrospray LC/MS/MS method for quantifying omapatrilat, a promising vasopeptidase inhibitor investigated at Bristol-Myers Squibb for hypertension and heart failure treatment, along with its complex metabolites in human plasma. His innovative work on automated sample preparation using pierceable caps further demonstrated his commitment to improving laboratory efficiency and reducing contamination risks. Across his publications, Khan's research reflects a consistent focus on advancing robust, high-throughput bioanalytical methodologies that underpin modern drug development pipelines.
Research Focus
Key Achievements
Top Papers
- 1
- 2
- 3