Paul E. Laibinis
Papers
1
Total Citations
22
H-Index
1
About
Paul E. Laibinis has made significant contributions to the development of advanced surface chemistry and analytical methodologies for biological imaging. His research focuses on creating innovative interfaces that simplify and enhance mass spectrometry-based proteomics. A key achievement is his work on prefabricated surfaces for imaging mass spectrometry (IMS), where he co-developed trypsin and MALDI matrix pre-coated targets. This innovation streamlines sample preparation by enabling on-slide enzymatic digestion of tissue proteins, directly facilitating the mapping of proteomic distributions within biological tissues—a technique detailed in his highly cited 2016 paper (22 citations). His broader impact lies in bridging surface chemistry with biomedical analysis, improving the accessibility and reproducibility of spatial proteomics. Laibinis’s work has been instrumental in advancing the practical application of MALDI-IMS, allowing researchers to visualize protein localization with greater ease and precision. His contributions continue to influence the fields of bioanalytical chemistry and tissue imaging, making complex molecular mapping more efficient for the scientific community.
Research Focus
Key Achievements
Top Papers
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