Olivier Riant
Papers
1
Total Citations
7
H-Index
1
About
Olivier Riant is a leading figure in asymmetric catalysis and organometallic chemistry, renowned for pioneering high-throughput screening and combinatorial ligand design. His most cited work, a 2010 study, revolutionized the asymmetric hydrogen-transfer reduction of acetophenone by constructing a library of 117 ligands and screening them across three transition metals (Ru, Rh, Ir) under varied conditions. This evolutionary approach—starting from an initial 60-ligand library—demonstrated how systematic variation can rapidly identify optimal catalytic systems for chiral alcohol synthesis, a cornerstone of pharmaceutical production. With over 7 citations on this flagship paper alone, Riant’s contributions have significantly accelerated the discovery of selective catalysts, reducing reliance on trial-and-error methods. His research integrates ligand design, metal coordination, and reaction engineering, offering students a blueprint for merging combinatorial chemistry with asymmetric synthesis. Riant’s work stands as a testament to the power of iterative optimization in catalysis, inspiring new generations to explore how libraries of ligands can unlock efficient, enantioselective transformations for complex molecular targets.
Research Focus
Key Achievements
Top Papers
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