Nicola Maffulli

Queen Mary University of London, University of Salerno

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About

Nicola Maffulli is a leading orthopaedic surgeon and researcher whose recent work centers on the transformative role of robotic-assisted technology in total knee arthroplasty (TKA). His research systematically addresses a critical clinical problem: up to 20% of TKA patients experience restricted motion or anterior knee pain, often due to suboptimal implant alignment. Maffulli’s major contributions include demonstrating how robotic-assisted TKA improves the accuracy of component positioning, thereby enhancing functional outcomes and reducing complications. His 2024 systematic review on functional alignment in robotic-assisted TKA has already garnered 40 citations, underscoring its immediate impact on surgical practice. He has also designed rigorous clinical trials, such as his 2023 protocol comparing robotic-assisted to freehand TKA, which aims to provide high-level evidence for adopting these technologies. Most recently, his 2025 perioperative comparison study continues to refine understanding of how robotics can better control stress forces on bearing surfaces. Through this body of work, Maffulli is helping to define the next standard of care in knee replacement surgery, making his research essential reading for orthopaedic surgeons, biomedical engineers, and clinical researchers focused on improving patient outcomes through precision surgery.