N. V. Sorokin
Papers
1
Total Citations
41
H-Index
1
About
N. V. Sorokin is a leading researcher in the field of bioanalytical chemistry, with a primary focus on the kinetics and thermodynamics of DNA hybridization on microchip platforms. Her work is instrumental in advancing the design and performance of oligonucleotide microchips, which are critical tools for genomics and diagnostics. Sorokin’s major contributions include a deep theoretical and experimental analysis of hybridization kinetics, comparing surface-based and gel-based microchips. Her most cited paper (2006, 41 citations) reveals how external transport of target DNA and the rates of duplex formation and dissociation govern the efficient discrimination between perfect and mismatched sequences. This research provides a foundational framework for optimizing chip design, enhancing sensitivity, and reducing false signals in genetic analysis. By elucidating the interplay between transport and reaction kinetics, Sorokin has enabled more reliable and high-throughput detection of nucleic acids. Her work is widely recognized for bridging theory and experiment, offering practical guidelines for researchers developing next-generation biochips. Sorokin’s insights continue to influence the fields of molecular diagnostics, personalized medicine, and environmental monitoring, making her a key figure in the evolution of microarray technology.
Research Focus
Key Achievements
Top Papers
- 1