Marie‐Claude Hepp‐Reymond

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About

Marie-Claude Hepp-Reymond has made pioneering contributions to the neuroscience of movement, with a particular focus on how the brain encodes kinematic parameters during both active and passive motion. Her research sits at the intersection of motor control, functional neuroimaging, and brain-machine interface (BMI) development. Through a series of highly cited studies, she has systematically investigated how sensorimotor regions process movement features such as forefinger velocity and displacement amplitude, revealing that the BOLD signal in these areas differentially encodes passive movement kinematics. Her 2018 paper on this topic has garnered 28 citations, while her 2014 reliability study on brain activation during robot-assisted arm movements—supported by an MRI-compatible robot—has been cited 17 times. Hepp-Reymond’s work is notable for its methodological rigor, particularly in delineating whole-brain BOLD responses to passive movement, as demonstrated in her 2013 study. By clarifying how cortical and subcortical regions encode movement parameters, her findings have important implications for advancing BMI systems, which could benefit from incorporating signals beyond the primary motor cortex. Her research continues to shape our understanding of sensorimotor integration and the neural basis of movement.