Jennifer Sturgis
Papers
1
Total Citations
15
H-Index
1
About
Jennifer Sturgis has pioneered the integration of high-throughput screening with single-cell analysis, fundamentally advancing how researchers evaluate drug efficacy at the most granular biological level. Her landmark work, "High-Throughput Secondary Screening at the Single-Cell Level" (2013, 15 citations), introduced an automated system that combines semiautomated preparation, high-speed sample collection, and real-time analytical tools to assess multiple functional responses from individual cells simultaneously. This innovation enables instantaneous, precise evaluation of compound dilutions across 384-well formats, dramatically accelerating the drug discovery pipeline while preserving the critical heterogeneity of cellular responses. Sturgis’s contributions are particularly impactful in oncology and pharmacology, where understanding variability among cells can determine treatment success. Her approach has been cited as a transformative method for secondary screening, bridging the gap between bulk assays and the nuanced reality of cellular behavior. By making single-cell functional analysis both practical and scalable, Sturgis has equipped researchers with a powerful tool to identify more effective therapeutics, reduce false positives, and ultimately bring precision medicine closer to clinical reality.
Research Focus
Key Achievements
Top Papers
- 1High-Throughput Secondary Screening at the Single-Cell Level15 citations · 2013