Jaycie DiDomenico
Papers
1
Total Citations
13
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1
About
Dr. Jaycie DiDomenico is a leading researcher at the forefront of sustainable chemistry, specializing in the valorization of biorenewable platform molecules through innovative high-throughput experimentation and continuous flow synthesis. Her work centers on transforming triacetic acid lactone (TAL)—a promising biobased building block—into high-value commodity chemicals. Dr. DiDomenico’s major contribution lies in pioneering the use of desorption electrospray ionization mass spectrometry (DESI-MS) as a rapid screening tool for chemical reactions, dramatically accelerating the discovery of new derivatives. This approach was validated in her highly cited 2020 study, which demonstrated the efficient conversion of TAL via aldol reactions and successfully translated the findings from microscale HTE to scalable continuous flow processes. With 13 citations, this work has established a new paradigm for integrating analytical chemistry with process intensification. Her achievements highlight a powerful synergy between analytical innovation and green engineering, positioning her as a key figure in the transition toward a bio-based chemical industry.
Research Focus
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Top Papers
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