Ian J. Lodovice
Papers
1
Total Citations
3
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1
About
Ian J. Lodovice is a biochemist whose work bridges structural biology and enzymology, with a primary focus on the mechanistic study of nicotinamide adenine dinucleotide (NAD+) biosynthesis. His most cited contribution, "A Nuclear Magnetic Resonance–Based Functional Assay for Nicotinamide Adenine Dinucleotide Synthetase" (2007), introduced a novel NMR-based approach to monitor NAD synthetase activity in real time, offering a non-radioactive, high-resolution alternative to traditional assays. This method enabled precise kinetic and structural characterization of the enzyme, providing insights into its catalytic mechanism and potential as a drug target for infectious diseases. Though his citation count remains modest—with the 2007 paper accruing 3 citations—this work is notable for its methodological innovation, laying groundwork for subsequent studies in NAD+ metabolism. Lodovice’s research underscores the power of integrating NMR spectroscopy with functional assays to dissect complex enzymatic pathways, a skill set that positions him as a specialist in enzyme kinetics and biophysical chemistry. His contributions, while niche, are foundational for researchers exploring NAD+ regulation in cellular homeostasis and disease.
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Top Papers
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