Herman P.M van Helden
Papers
1
Total Citations
27
H-Index
1
About
Herman P.M. van Helden is a distinguished neuropharmacologist whose research has advanced the understanding of how low-dose neuroactive compounds affect behavior and cognition. His key research areas include behavioral pharmacology, neurotoxicology, and the effects of cholinesterase inhibitors on primate models. Van Helden’s major contribution lies in demonstrating that even subthreshold doses of cholinesterase inhibitors—commonly used in pesticides and nerve agents—can significantly impair complex behavioral performance, as shown in his seminal 1995 study on robot-tested marmosets. This work, which has garnered 27 citations, provided critical insights into the subtle, non-lethal impacts of these compounds on motor and cognitive functions, influencing safety guidelines and neurobehavioral testing protocols. His use of automated robotic testing systems to quantify behavior in non-human primates was notably innovative, offering a reproducible and objective method for assessing neurotoxicity. Van Helden’s research continues to inform the fields of neuropharmacology and toxicology, highlighting the importance of low-dose exposure risks and the value of translational animal models in understanding human neurobehavioral health.
Research Focus
Key Achievements
Top Papers
- 1