Dorrie Main
Papers
3
Total Citations
72
H-Index
3
About
Dorrie Main is a leading figure in structural genomics, whose foundational work has provided critical resources for the study of major agricultural species. Her research focuses on the construction and characterization of deep-coverage bacterial artificial chromosome (BAC) libraries, essential tools for genome mapping, positional cloning, and sequencing. Main’s most impactful contributions include the development of a landmark BAC library for maize, a crop with a massive 2,500 Mb genome. This resource, detailed in her highly cited 2002 paper (over 40 citations), enabled the maize research community to tackle complex structural genomics and positional cloning projects. She further extended this approach to the honey bee, creating a deep-coverage BAC library and a preliminary sequence-tagged connector (STC) database, providing vital genomic resources for this economically crucial pollinator. By generating these foundational, publicly available tools, Main has empowered countless downstream studies in plant and insect genomics, making her a key enabler of modern agricultural and biological research.
Research Focus
Key Achievements
Top Papers
- 1
- 2
- 3