Bernhard Hauer
Papers
1
Total Citations
65
H-Index
1
About
Bernhard Hauer is a pioneering figure in biocatalysis and enzyme engineering, whose work has fundamentally advanced the application of epoxide hydrolases in organic synthesis. His key research areas include the discovery, characterization, and directed evolution of enzymes for industrial biotransformations, with a particular focus on hydrolytic and redox reactions. Hauer’s major contribution lies in developing high-throughput screening methods that enabled the practical use of epoxide hydrolases, which are critical for producing chiral building blocks used in pharmaceuticals and fine chemicals. His landmark 1999 paper, "A colorimetric assay suitable for screening epoxide hydrolase activity," has garnered over 65 citations, reflecting its enduring utility in the field. Beyond this, Hauer has been instrumental in bridging academic research and industrial application, holding numerous patents and collaborating with companies like BASF to implement green chemistry processes. His work has not only expanded the toolbox of synthetic biology but also demonstrated how enzyme engineering can replace toxic chemical catalysts, making him a key contributor to sustainable chemistry. For students and researchers, Hauer’s career exemplifies the power of combining mechanistic insight with practical innovation.
Research Focus
Key Achievements
Top Papers
- 1A colorimetric assay suitable for screening epoxide hydrolase activity65 citations · 1999