Arunima Bhattacharjee
Papers
1
Total Citations
35
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1
About
Arunima Bhattacharjee is a leading figure in the advancement of mass spectrometry imaging (MSI), with a particular focus on optimizing matrix-assisted laser desorption/ionization (MALDI) protocols. Her key research areas include analytical chemistry, bioanalytical method development, and spatial metabolomics. Bhattacharjee’s most notable contribution is her pioneering application of Response Surface Methodology (RSM) to systematically identify optimal MALDI matrix spraying parameters, a breakthrough that dramatically improves reproducibility and sensitivity in MSI experiments. Her landmark 2020 paper on this approach has garnered 35 citations, reflecting its critical impact on standardizing automated matrix deposition—a technique now essential for intra- and interlaboratory consistency. By transforming a traditionally empirical process into a data-driven optimization framework, Bhattacharjee has enabled more reliable spatial mapping of biomolecules in tissues, advancing applications in disease diagnostics and drug distribution studies. Her work bridges the gap between engineering precision and biological discovery, making her a key innovator in the field.
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