Anke M. Mulder

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About

Anke M. Mulder has made significant contributions to structural biology, particularly in advancing automation for single-particle electron microscopy (cryo-EM). Her most-cited work, "Automation in Single-Particle Electron Microscopy" (2010), has garnered 24 citations and addresses a critical bottleneck in the field: the need for high-throughput, reproducible data collection. By developing automated workflows for image acquisition and processing, Mulder’s research has helped democratize cryo-EM, enabling researchers to resolve macromolecular structures with greater efficiency and accuracy. Her efforts have directly supported the transition of cryo-EM from a specialized technique to a mainstream tool for structural determination, impacting studies of proteins, viruses, and molecular complexes. Beyond this key paper, Mulder’s work underscores her role in integrating computational methods with experimental biology, streamlining processes that were once labor-intensive. Her contributions continue to influence the design of automated pipelines, making high-resolution structural analysis more accessible to the scientific community. For students and researchers exploring cryo-EM, Mulder’s research exemplifies how automation can accelerate discovery in structural biology.