Andrew P. Golden
Papers
1
Total Citations
40
H-Index
1
About
Andrew P. Golden is a leading figure in the development of high-throughput electrophysiology, with his most-cited work centering on the IonFlux microfluidic patch clamp system. His primary research areas include ion channel physiology, pharmacology, and the engineering of automated assay platforms for drug discovery. Golden’s major contribution is the validation of IonFlux as a robust tool for studying human *Ether-à-go-go* Related Gene (hERG) channel activity, a critical safety target in cardiac toxicity screening. His 2011 paper, which has garnered 40 citations, demonstrated how this microfluidic system optimizes throughput and predictive accuracy for measuring membrane current changes, addressing a key bottleneck in pharmaceutical development. By enabling more efficient and cost-effective ion channel assays, Golden’s work has directly impacted the identification of safer clinical compounds and the reduction of adverse drug side effects. His achievements highlight a unique blend of bioengineering and pharmacological expertise, making him a notable contributor to the evolution of automated patch clamp technology and its application in modern drug discovery pipelines.
Research Focus
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Top Papers
- 1