Alessandro Spilotros
Papers
1
Total Citations
611
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1
About
Alessandro Spilotros is a leading figure in structural biology, specializing in the development and application of small-angle X-ray scattering (SAXS) for macromolecular solutions. His most impactful work centers on advancing synchrotron beamline technology, most notably through his instrumental role at the P12 beamline (PETRA III, DESY). As a co-author of the highly cited 2015 paper describing this beamline (611 citations), Spilotros contributed to a versatile, automated platform that revolutionized biological SAXS experiments. This facility, optimized for high-throughput data collection and equipped with innovative scatterless slits, dramatically reduced parasitic background noise, enabling more precise structural analysis of proteins and complexes in solution. Beyond beamline design, his research has pushed the boundaries of automation and sample environments, making cutting-edge structural biology more accessible. With a career defined by technical innovation and collaborative impact, Spilotros has helped shape modern SAXS methodology, empowering researchers worldwide to probe the dynamic structures of biomolecules with unprecedented clarity and efficiency.
Research Focus
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Top Papers
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