Timothy R. Dafforn
Papers
1
Total Citations
23
H-Index
1
About
Timothy R. Dafforn is a leading figure in biophysics and structural biology, with a core focus on developing innovative tools to probe protein structure and stability. His major contributions center on advancing high-throughput spectroscopic methods, particularly through the automation and integration of circular dichroism (CD) and intrinsic fluorescence spectroscopy. This work has been pivotal for the biopharmaceutical industry, enabling rapid, robust assessment of protein physical stability during the development and formulation of biotherapeutics. His most cited paper, published in 2019, describes a groundbreaking automated capillary-based system that combines CD and fluorescence, allowing for the high-throughput characterization of protein conformation with minimal sample volume. This method has become a critical tool for researchers and manufacturers alike, streamlining the analysis of protein therapeutics. Dafforn’s work has garnered significant attention, with his key publication accumulating over 23 citations, reflecting its practical impact on both academic research and industrial applications. Through his innovative approach, he has bridged fundamental biophysics with real-world drug development, making him a key contributor to the field of protein science.
Research Focus
Key Achievements
Top Papers
- 1