Steven M. Cramer
Papers
1
Total Citations
27
H-Index
1
About
Steven M. Cramer is a distinguished researcher whose work sits at the intersection of bioseparations, chromatography, and biopharmaceutical purification. His research has made meaningful contributions to the downstream processing of biologics, with a particular focus on developing innovative chromatographic strategies for the purification of complex biomolecules, including monoclonal antibodies (mAbs). Among his notable contributions is the application of selective desorption chromatography using ceramic hydroxyapatite (CHT) systems for the separation of monomeric mAbs from aggregates and other post-protein A step impurities — a technically challenging problem with direct relevance to biopharmaceutical manufacturing. This work, which has garnered 27 citations, demonstrated the power of combining robotic liquid handling systems with parallel batch screening to accelerate method development, offering both efficiency and scalability to industrial bioprocessing workflows. Cramer's research is valued for bridging fundamental separation science with practical biomanufacturing challenges, making his findings accessible and applicable to both academic researchers and industry practitioners. His contributions continue to inform how the field approaches the purification of therapeutic proteins, helping to improve both product quality and process efficiency in an era where biologics are increasingly central to modern medicine.
Research Focus
Key Achievements
Top Papers
- 1