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Mining predicted crystal structure landscapes with high throughput crystallisation: old molecules, new insights

Peng Cui, David P. McMahon, Peter R. Spackman, Ben M. Alston, Marc A. Little, Graeme M. Day, Andrew I. Cooper

Year
2019
Citations
99
Access
Open access

Abstract

New crystal forms of two well-studied organic molecules are identified in a computationally targeted way, by combining structure prediction with a robotic crystallisation screen, including a ‘hidden’ porous polymorph of trimesic acid.

Keywords

CrystallizationThroughputMoleculeCrystal structure predictionCrystal structureMaterials scienceCrystallographyChemical physicsChemistryComputer science

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