Exoscopic Transoral Supraglottic Laryngectomy

摘要

This article, accompanied by technical notes and video, presents a case of an 85-year-old patient with a cT2N0 laryngeal squamous cell carcinoma treated using CO2 transoral laser exoscopic surgery (TOLES). The procedure achieved en bloc tumor removal with negative margins, preserving laryngeal and swallowing functions, demonstrating TOLES as a viable alternative to traditional microsurgery with enhanced visualization and ergonomics. Laryngoscope, 135:744–747, 2025 A substantial turning point in the surgical management of laryngeal squamous cell carcinomas (SCC) was the introduction of carbon dioxide transoral laser microsurgery (CO2 TOLMS),1 which involves the use of an operating microscope that provides an excellent magnified view of the surgical field. Recently, the refinement of exoscopic systems has provided the head and neck surgeon with a new magnification tool, potentially competing with the operative microscope in various procedures, from microvascular free flap anastomosis2 to transoral surgery.3, 4 In particular, coupling between a 4K-3D exoscopic system and CO2 laser micromanipulator, when performing transoral laser laryngeal surgery, seems to be noninferior to the operative microscope in terms of surgical time, resection radicality, and precision, with some advantages in terms of intuitivism, maneuverability, ergonomics, and ease of alignment.5 In this setting, the surgeon is in close contact with the laryngoscope inlet, looking at the surgical field in a 3D high-definition screen, without bulky instruments obstructing the space of maneuver, and without the need of keeping the head constantly in contact with the microscope eyepieces.6 This subjectively improves the surgeon's comfort and ergonomics,3 favoring bimanual tissue manipulation while maintaining an optimal magnified stereoscopic visualization of the larynx. Moreover, using 3D glasses, the surgeon's assistant(s), as well as all the operatory room staff, can easily follow the entire procedure with the same surgical field of view of the first operator. This improves the possibility for assistants to help during some crucial parts of the procedure. The significant magnification capability (up to 15× zoom) is particularly useful to approach supraglottic, glottic, and subglottic regions, keeping optimal illumination even at high depth of field. Furthermore, during magnification, it is possible to digitally move the field of view using a separate control joystick, without the need to physically move and adjust the exoscope. On the other hand, the robotic arm (ARTip cruise robotic system, Karl Storz, Tuttlingen, Germany), on which the exoscope is mounted in the most recent version of the VITOM 3D, makes it possible for the surgeon to easily modify the observant's perspective using a dedicated joystick (IMAGE1 PILOT, Karl Storz, Tuttlingen, Germany). To date, no clinical video report has been published regarding the application of the CO2 transoral laser exoscopic surgery (TOLES) for treatment of laryngeal SCC. In this case video, the authors sought to point out the feasibility and strengths of this technology in transoral surgery. In this case video, the authors sought to highlight the feasibility and strengths of transoral exoscopic laser resection for the treatment of a supraglottic laryngeal carcinoma. The exoscopic visualization guaranteed a bright and wide view of the surgical field during the entire procedure, thus simplifying the zooming process during the most challenging steps. In this setting, the surgeon is in close contact with the laryngoscope inlet, looking at the surgical field in a 3D high-definition screen, without bulky instruments obstructing the space of maneuver. The patient who underwent this procedure signed an informed consent to publication through Wiley standard form. We proposed the employment of CO2 TOLES as alternative to CO2 TOLMS in treatment of a supraglottic cancer located in the supra-hyoid portion of the epiglottis and extended t