Enhancement of selectivity of electrochemical detectors by kinetic discrimination in flow-injection systems

摘要

Appropriate design of flow-injection (FI) manifold and selection of suitable detectors may provide additional changes in the selectivity of the FI response compared to conventional nonflow measurements. As an example of such systems, based on data from the literature and our own experimental data, the potentiometric detection with different ion-selective electrodes and two different amperometric systems are discussed. Selectivity changes in flow-injection analysis (FIA) systems for ion-selective membrane electrodes depend on relative response to interferences observed in batch measurements. Simultaneous detection of pesticides is shown as an example of an amperometric FIA system with a bilayer lipid membrane working electrode. Simultaneous detection of lactate and ascorbate is shown in an FIA system with amperometric biosensing detection. © 2000 John Wiley & Sons, Inc. Lab Robotics and Automation 12:205–215, 2000