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MX2: a high-flux undulator microfocus beamline serving both the chemical and macromolecular crystallography communities at the Australian Synchrotron

David Aragão, Jun Aishima, H. Cherukuvada, Robert Clarken, M Clift, Nathan Cowieson, Daniel J. Ericsson, Christine L. Gee, Sofia Macedo, Nathan Mudie, Santosh Panjikar, Jason R. Price∥, Alan Riboldi‐Tunnicliffe, Robert Rostan, Rachel Williamson, Thomas Tudor Caradoc-Davies

发表年份
2018
引用次数
543
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摘要

MX2 is an in-vacuum undulator-based crystallography beamline at the 3 GeV Australian Synchrotron. The beamline delivers hard X-rays in the energy range 4.8–21 keV to a focal spot of 22 × 12 µm FWHM (H × V). At 13 keV the flux at the sample is 3.4 × 10 12 photons s −1 . The beamline endstation allows robotic handling of cryogenic samples via an updated SSRL SAM robot. This beamline is ideal for weakly diffracting hard-to-crystallize proteins, virus particles, protein assemblies and nucleic acids as well as smaller molecules such as inorganic catalysts and organic drug molecules. The beamline is now mature and has enjoyed a full user program for the last nine years. This paper describes the beamline status, plans for its future and some recent scientific highlights.

关键词

BeamlineUndulatorSynchrotronOpticsSynchrotron radiationPhysicsMaterials scienceBeam (structure)

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