Sonja Stoelzle
Papers
1
Total Citations
59
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1
About
Sonja Stoelzle is a pioneering figure in the field of ion channel electrophysiology and drug discovery, with a career dedicated to advancing high-throughput screening technologies. Her research focuses on the development and application of automated patch-clamp systems, particularly the Port-a-Patch and Patchliner platforms, which have revolutionized the study of ion channel dysfunction—a key factor in numerous acute and chronic disorders. Her landmark 2009 paper, "Port-a-Patch and Patchliner: High Fidelity Electrophysiology for Secondary Screening and Safety Pharmacology," has garnered 59 citations, underscoring its foundational role in enabling functional, high-quality drug screening for ion channel targets. Stoelzle’s major contribution lies in bridging the gap between traditional manual patch-clamp techniques and high-throughput automation, allowing researchers to efficiently assess drug safety and efficacy in secondary screening. Her work has been instrumental in transforming ion channels into more tractable drug targets, impacting both academic research and pharmaceutical development. Through her innovative platforms, Stoelzle has empowered scientists to explore ion channel physiology with unprecedented fidelity, making her a key architect of modern electrophysiological screening.
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Top Papers
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