Sae Kishi
Papers
1
Total Citations
3
H-Index
1
About
Sae Kishi is a computational biophysicist whose work bridges the nanoscale worlds of DNA nanotechnology and molecular dynamics simulation. Her primary research focuses on the structural behavior of DNA origami—complex, self-assembling nanostructures—in realistic aqueous environments. In her landmark 2018 study, Kishi pioneered a novel technique using an inorganic supporting film to perform all-atom molecular dynamics simulations of flat-shaped DNA origami, tackling systems of over 16 million atoms including explicit water molecules. By leveraging GPU-accelerated simulation engines, she successfully addressed the conformational dynamics of these massive biomolecular assemblies, a feat previously considered computationally prohibitive. This work, which has garnered 3 citations, provides critical insights into the stability and flexibility of DNA nanostructures for applications in drug delivery and nanorobotics. Kishi’s contributions are particularly notable for pushing the boundaries of computational scale in biophysics, demonstrating that even the largest DNA-based constructs can be modeled with atomic precision. Her research continues to inspire new approaches to simulating complex biomolecular systems, making her a rising figure in computational structural biology.
Research Focus
Key Achievements
Top Papers
- 1